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A body of studies is showing that a blood marker called p-tau217 can forecast an elevated risk of cognitive impairment in healthy older adults years before symptoms appear. The evidence is not yet clinical-ready, but it is guiding trials that aim to slow or prevent Alzheimer’s disease and is being tested in Scotland’s primary care setting.
Scotland is piloting BriDGe, a project using p-tau blood tests in over 50 GP practices to speed Alzheimer’s diagnosis, with up to 500 patients referred. Experts say this could shift dementia care toward earlier intervention with better access to treatment and support.
The Gordie Howe International Bridge opens to traffic amid US-Canada tensions after Donald Trump imposes a 50% tariff on most Canadian goods. Canada has canceled a joint opening ceremony, citing the tariff action, while Canada plans its own ceremony. The controversy centers on a revised deal for bridge ownership and profit sharing, with officials signaling a tense start to the project’s operational phase.
Protesters who blocked a San Francisco bridge amid a Gaza-related action have been convicted on misdemeanors after a short trial. Seven defendants faced charges including unlawful assembly and false imprisonment; a new trial on conspiracy was dropped. Each received a 30-day sentence, six months of probation, and a $1,000 fine, with time served reducing jail time. Most defendants had previously been offered diversion.