The world’s largest independent cancer research charity in the UK
England has authorised Enhertu for routine NHS use for HER2‑low metastatic breast cancer, ensuring access for about 1,000 women annually. The decision follows a previous rejection over cost‑effectiveness and builds on a deal between NICE and drug makers AstraZeneca and Daiichi Sankyo. Scotland has already provided access since 2023.
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AstraZeneca has announced that Wainua, its gene-silencer drug for transthyretin-mediated amyloid cardiomyopathy, did not meet its primary endpoint in a phase 3 trial. The news triggers a sharp stock drop and prompts investors to rethink the company’s long-term growth targets and the strength of its pipeline.
A UK NHS study indicates focal therapy provides durable long‑term cancer control for many prostate cancer patients, with just two of 3,477 men dying from prostate cancer a decade after treatment and lower side‑effects. The government is expanding access to more centres.
International researchers find inherited genetics influence how cancers evolve after DNA damage, affecting tumour growth and mutation patterns. The Edinburgh-led work, published in Nature, underlines implications for screening, diagnosis and personalised treatment across populations.
Cambridge and ICR researchers show NICE criteria miss up to 95% of women under 50 who will develop breast cancer within 10 years. A new model called Boadicea identifies eight times as many high-risk women, prompting calls for review and investment to implement multifactorial risk assessment across the NHS.
A Scottish athlete’s plea for a national brain cancer lead has intensified calls for a faster, more coordinated national cancer plan. Across the UK, brain tumours remain a leading cause of death for under-40s, with funding and access to treatment under scrutiny.
Lucy Davis has disclosed a Stage 4 breast cancer diagnosis that has metastasised to her bones. She states the cancer is incurable and that chemotherapy is no longer an option. She will continue living as fully as possible while seeking privacy for her family.
Lucy Davis has revealed an incurable breast cancer diagnosis with metastasis to her bones. She has thanked fans for support and shared a light moment skateboarding to show she remains positive. The message has drawn messages of love from fellow actors and family.
A comprehensive review links vaping to respiratory and other health harms in children and young people, with warnings about pregnancy exposure. UK officials are urged to extend restrictions to limit flavours and marketing to protect youths while continuing to support smoking cessation for adults.
A wave of studies finds that AI analysis of mammograms can identify cardiovascular risks in women, including hypertension, coronary heart disease and stroke, alongside breast cancer screening. Researchers say mammograms could become a dual-purpose tool for early cardiovascular risk detection, prompting earlier intervention.
The NHS has launched a program to send self‑testing HPV kits to eligible women aged 30–65 who have missed cervical screening appointments. The at‑home swabs test for high‑risk HPV; negative results lead to in‑person follow‑ups. The phased rollout aims to boost screening uptake and support the 2040 elimination target.
The Corte Madera Town Council votes to advance an ordinance banning tobacco and nicotine products, including vapes, with a transition through Jan. 31, 2027. Residents may keep possessions. Public comment highlighted concerns from students and families affected by tobacco-related illness.
A set of patients with various cancers across the UK and Europe are living with ongoing treatment. A colon cancer patient uses AI tools to track symptoms and medical records; a breast cancer survivor with a CHEK2 mutation faces life-long therapy; another woman battles brain tumours and metastatic disease, while a patient with uterine cancer reflects on caregiving and diagnosis.
A UK study involving nearly a million adults finds that drinking beverages at very hot temperatures increases the risk of esophageal squamous cell carcinoma (SCC). The risk rises with frequency, with six or more hot drinks daily, though overall risk remains small. Researchers urge cooling beverages before drinking.