Open-access medical journal from the American Medical Association
A Japanese approval for Telomelysin offers a gentler option for esophageal cancer patients ineligible for surgery. Other studies show CAR T-cell therapy remains transformative for certain cancers, while nanotechnology and immunotherapies highlight ongoing progress with meaningful patient impact.
A set of recent reports cover long Covid rehabilitation, a Parkinson’s diagnosis for Bruce Foxton of The Jam, and Lyme disease campaigning by a Scottish MSP. Also covered are ulcerative colitis coupled with PSC in a Birmingham mother and ongoing chronic illness advocacy in media.
A JAMA Network Open study finds the vaccine reduces COVID-19-related hospitalizations by about 55% and lowers visits to emergency departments by 50%. The paper has drawn attention because of past political interference in CDC publishing decisions. The study uses a test-negative design and is part of ongoing assessments of vaccine performance amid evolving viral strains.
Vivani Medical is developing a long-acting semaglutide implant to deliver GLP-1 therapy over months, potentially replacing injections. Novo Nordisk is evaluating the device to improve adherence and reduce weight regain, but regulatory and cost questions remain as trials proceed.