Leading general medical journal and editorial voice of the AMA
Researchers have published long-term data showing that very high blood levels of the tau marker p‑tau217 predict a 38% risk of cognitive impairment within five years and 78% within ten. Trials are using the test to recruit volunteers while Scotland has started a primary‑care rollout of p‑tau testing to study real‑world use.
The newly released texts show Fauci discussing early vaccination risks in pregnancy, while officials acknowledge uncertainty in 2021. Since then, large studies have found no link between COVID-19 vaccines and miscarriage or adverse pregnancy outcomes. The conversation has become a political flashpoint as Republican lawmakers push into the public sphere.
Josh Kushner has issued his first public statement on the collapsed FIFA Forward Enterprise proposal, saying he still supports its aims but would not have invested had he known how the process would unfold. UEFA has filed US court papers seeking document production and depositions from Kushner and Thrive as it prepares possible criminal mismanagement claims against FIFA president Gianni Infantino.
Major US medical societies have issued unified guidance this week for flu, COVID-19 and RSV vaccines after the CDC’s advisory process has been disrupted. Updated COVID shots have FDA approval and manufacturers are shipping doses, but legal and policy disputes over federal recommendations continue to leave states and insurers uncertain about timing and coverage.