French pharma giant shaping global healthcare
The NHS in England and Wales has approved teplizumab, the first drug that can delay onset of type 1 diabetes. The immunotherapy offers up to three extra years before symptoms require lifelong insulin, with rollout backed by NICE and a commercial deal with Sanofi.
The FDA has approved Lipfendra, Merck’s oral PCSK9 inhibitor, to lower LDL cholesterol in patients on statins. Trials show ~55-60% LDL reductions; the pill will be sold at about $315/month and must be taken on an empty stomach. Analysts see potential peak sales in the billions as injectable rivals face competition and access barriers.
Companies like Kalshi are expanding prediction markets to biotech trials, linking drug trial outcomes to tradable contracts. Bloomberg and The Guardian report Kalshi’s pilot, its safeguards, and regulatory concerns, as markets push for open data on trial probabilities amid regulatory decisions.