A filovirus species driving severe hemorrhagic fever outbreaks
Frontline workers at Ituri’s Ebola response facilities have struck over unpaid wages as the Bundibugyo outbreak expands to more provinces. The situation adds strain to an already overwhelmed health system, with clinics at capacity and mistrust hampering containment efforts. New cases have been confirmed in Haut-Uele and Tshopo, raising the outbreak’s regional footprint.
The Bundibugyo-strain Ebola outbreak in the Democratic Republic of the Congo has reached over 4,000 confirmed cases with about 1,900 deaths, and is progressing at an unprecedented rate. Health workers face unpaid wages, security threats and misinformation while WHO and Africa CDC coordinate trials and vaccination efforts amid a volatile security situation.
The DRC has recorded the largest-ever Bundibugyo Ebola outbreak, with more than 5,600 confirmed cases and over 2,700 deaths, and international agencies are racing to respond. WHO and partners have allocated 70,000 Ervebo doses—20,000 for a Phase III trial and 50,000 for frontline workers—while CEPI has awarded up to $16.5m to advance a Minapharm Bundibugyo vaccine into early human trials. Uganda has received MBP134 antibody vials as a precautionary measure.
The Bundibugyo strain of Ebola is spreading across eastern Congo, with thousands of cases and deaths reported. Health workers are receiving Ervebo under compassionate-use rules as vaccination campaigns expand amid ongoing insecurity and displacement. WHO warns the outbreak remains out of control while vaccines are being tested for effectiveness against Bundibugyo.
The Ebola outbreak in eastern Congo has expanded to two new zones—Biena and Manguredjipa—fueling a surge in cases and deaths as health workers face security challenges. Vaccination of frontline workers has begun with Ervebo, and the WHO warns the outbreak is out of control with cross-border risks rising.