A deadly filovirus causing severe hemorrhagic fever in humans
The Bundibugyo-strain Ebola outbreak in the Democratic Republic of the Congo has reached over 4,000 confirmed cases with about 1,900 deaths, and is progressing at an unprecedented rate. Health workers face unpaid wages, security threats and misinformation while WHO and Africa CDC coordinate trials and vaccination efforts amid a volatile security situation.
The Democratic Republic of Congo has recorded an unprecedented Bundibugyo Ebola outbreak that has spread across six provinces and produced more than 5,000 confirmed cases and over 2,600 deaths. WHO and partners have allocated 70,000 Ervebo vaccine doses—20,000 for a Phase III trial and 50,000 for frontline workers—while CEPI has funded a Bundibugyo-specific vaccine and the US has sent MBP134 treatment vials to Uganda.
The Bundibugyo strain of Ebola is spreading across eastern Congo, with thousands of cases and deaths reported. Health workers are receiving Ervebo under compassionate-use rules as vaccination campaigns expand amid ongoing insecurity and displacement. WHO warns the outbreak remains out of control while vaccines are being tested for effectiveness against Bundibugyo.
The Ebola outbreak in eastern Congo has expanded to two new zones—Biena and Manguredjipa—fueling a surge in cases and deaths as health workers face security challenges. Vaccination of frontline workers has begun with Ervebo, and the WHO warns the outbreak is out of control with cross-border risks rising.