A coastal Southern California city at the border with Mexico, eighth-most populous in the U.S.
This week has seen several medical research and regulatory developments. Insilico Medicine has reported that its experimental drug rentosertib changed blood‑protein patterns that aging clocks read as three to four years younger in a small trial. Stanford teams have published studies showing they can grow hindbrain neurons separately and implant human cortical organoids into mice. The US health department has appointed permanent directors for three FDA centers.
Multiple US states are pausing or regulating Flock Safety’s ALPR network amid privacy concerns, with ongoing debates on data use and accountability for law enforcement.
Survivors of climate disasters have built a nationwide support and advocacy network, Extreme Weather Survivors, now counting more than 2,500 members. The group provides guidance and emotional support while lobbying lawmakers as climate disasters intensify.
Belugas relocated from Marineland to US and Spain are dying at Chicago’s Shedd Aquarium and other sites. Osiris, a 26-year-old female, died at Shedd after arriving with other rescued whales. Two other belugas, Peekachu and Rain, died at Shedd; Jelly Bean died in Valencia. The deaths highlight vulnerabilities after the controversial Marineland closure.
Acting Navy Secretary Hung Cao has told Senator Kirsten Gillibrand that eight sailors across the USS Abraham Lincoln strike group have attempted suicide during a record-long deployment. The carrier has spent about 286 days at sea, faced supply and hygiene problems, and disembarked in Thailand on 1 September; Cao said no deaths occurred and medical and mental-health care remained available aboard.
Two giant pandas, Ping Ping and Fu Shuang, have been pledged to Zoo Atlanta as part of a long-running diplomatic program. Their arrival signals renewed US-China soft-power ties amid ongoing discussions on AI and trade during Xi Jinping’s state visit with President Trump. The animals will undergo quarantine before public viewing, with timelines for appearance at the zoo still unconfirmed.
Berkshire Hathaway has nearly doubled its stake in Lennar to about 25.4 million shares, valued at roughly $2.1 billion, as the housing market slows and mortgage rates stay high. The purchases occurred between Sept. 17 and Sept. 21, with additional buys reported later in the week. Lennar’s quarterly results were weak, and Berkshire’s move is seen as a classic value play within the portfolio, guided by Ted Weschler.
A federal jury in California has ruled that Apple infringed two Taction Technology patents related to haptic feedback. The verdict comes after a long-running case that began in 2021 and was revived on appeal, with Apple planning to appeal the decision.
The San Diego Padres have swept the Chicago Cubs in the wild-card series, holding Chicago to just one run across two games. The Padres now face the Milwaukee Brewers in the NLDS as they seek to maintain their hot streak and push toward a first World Series since 1998.
The USS Theodore Roosevelt has left San Diego and is headed toward the Middle East. Officials say the move could allow three carrier strike groups in the region, but no final destination has been decided yet. Bloomberg reports a broader buildup could accompany such a deployment.
California officials have announced a $272.5 million settlement with Lyft over allegations that drivers were misclassified as independent contractors from 2016 to 2020, denying minimum wage and other protections. The majority of funds will go to drivers through a third‑party administrator, pending court approval. Uber’s case remains ongoing.
Jake Cronenworth and Xander Bogaerts drive the Padres to a narrow win in Milwaukee, keeping hope alive in the NLDS as Michael King secures the save and Milwaukee faces bullpen questions ahead of Game 4.
President Donald Trump has suggested at a Nebraska rally that higher fuel prices from the US‑Israel war with Iran are "a small price to pay," saying "they can take out a city — let them take out Los Angeles, let them take out San Diego." California leaders have called the comments "deranged" and "dangerous," while the White House has labelled the reaction a "media freakout."
The USS Abraham Lincoln has returned to San Diego after a months-long deployment diverted from a Pacific return to support operations against Iran. Sailors faced food shortages, mental-health strain, and extended sea duty, while officials defend the mission amid public scrutiny and rising domestic concerns.
The USS Abraham Lincoln has returned to San Diego after a record 265 days at sea in support of operations related to the Iran conflict, bringing home roughly 5,000 sailors and Marines. Families welcomed loved ones with emotional reunions; many report stress and food shortages aboard the carrier during the deployment. The Navy has awarded the Presidential Unit Citation amid acknowledgment of fatigue and challenges faced by the crew.